CRPS clinical pathway
Finally, a clear path forward for CRPS
If you are living with CRPS and still feel uncertain about what to do next, our specialized team in Verona, Italy is here to help. We offer a structured infusion-based treatment protocol centered on Neridronate, with direct access to the clinic and clear guidance from the very first step.
Direct medical care • Evidence-based treatment • No intermediaries
No obligation. No pressure. Just clear information and direct contact with the clinic.
Tommaso Martella
Patient Care Manager and Clinical Operations Coordinator
“You will speak directly with me during your first free video call.”
When you still don’t have clear answers
Living with CRPS can feel exhausting, confusing, and deeply isolating
Many patients come to us after seeing multiple specialists, trying different treatments, and still feeling they do not have a clear plan. If that is where you are today, our role is to help you understand whether a more structured, evidence-based pathway may be appropriate for your case.
No pressure. No false promises. Just clarity, direct medical guidance, and a serious clinical evaluation.
A specialized clinic for patients seeking clarity
Why patients from the United States come to PSV
For more than 10 years, Poliambulatorio Specialistico Verona has welcomed patients from the United States seeking clearer answers, a more precise clinical assessment, and access to a structured CRPS pathway. In the last decade, PSV has supported more than 200 U.S. patients.
Direct access
Patients are in direct contact with the clinic from the very beginning. No agencies, no coordinators, no medical-travel services between you and our team.
English-speaking team
Clear communication, transparent information, and direct interaction in English with the team involved in the treatment pathway.
Focus on treatment
A focus on treatment, not on selling a travel experience. Practical guidance when needed, while keeping the medical pathway at the center.
Core protocol
4 ×
Neridronate
IV infusions
May be strengthened with
Clodronate infusions
Additional bisphosphonate support based on clinical profile
Vitamins & coenzymes
Infusion-based metabolic and cellular support
Rehabilitation
Functional recovery and continuity of care
Gut microbiota
Targeted nutrition and microbiota modulation
Each element is considered only when clinically appropriate for the individual patient.
A structured, infusion-based clinical pathway
The CRPS infusion protocol
CRPS is a complex condition, and for that reason we do not reduce it to pain alone.
At the center of our protocol is a structured infusion-based pathway built around a cycle of 4 intravenous Neridronate infusions.
Based on the clinical profile of each patient, the treatment pathway may also be strengthened with additional infusion-based and supportive elements.
The goal is not to offer a generic package. The goal is to build a serious, medically guided pathway around the individual patient.
More than a standard protocol
Precision medicine and multidisciplinary care
PSV works with a precision medicine approach, meaning that the team looks at the patient’s clinical history, biological profile, functional status, and overall complexity before defining the pathway.
Your case may involve expertise from rheumatology, neurology, rehabilitation, physiotherapy, nutrition, and dedicated expertise in gut microbiota modulation. This allows us to create a more personalized path, with treatment choices explained clearly and adapted to the individual case.
Meet the scientific and clinical team
A multidisciplinary structure supporting the CRPS pathway
At PSV, the CRPS pathway is supported by a multidisciplinary clinical structure that combines medical direction, treatment eligibility, rehabilitation, infusion care, nutrition, and gut microbiota expertise.
Scientific board
Fabrizio Martella, MD
Medical Director and Scientific Coordinator
Oversees the clinical and scientific direction of the CRPS pathway and helps ensure the overall coherence of the treatment model.
Luca Dalle Carbonare, MD, PhD
Clinical Eligibility Director
Supervises patient selection and clinical appropriateness for treatment, helping define whether the pathway is suitable for each case.
Ermes Vedovi, MD
Director of Rehabilitation and Neurorehabilitation
Leads the rehabilitation component of the pathway.
Chiara Gentili
Nutritional and Gut Microbiota Specialist
Supports the pathway with dedicated expertise in nutrition, nutraceutical support, and gut microbiota modulation.
Luigi Delaini
Manual Therapy Specialist
Contributes manual therapy expertise within the broader rehabilitation framework when clinically appropriate.
Paolo Manganotti, MD, PhD
Neurology and Electroneurophysiology Supervisor
Provides neurological supervision and high-level expertise in electrophysiology and research.
Clinical support team
Marzia Milani
Patient Care Manager and Clinical Infusion Specialist
Supports infusion care and patient coordination throughout the treatment pathway.
Chiara Pezzo
Infusion Nurse Specialist
Supports infusion therapies and day-to-day clinical assistance during treatment.
Laura Ambra
Critical Care Nurse Specialist
Provides nursing support for patients requiring careful monitoring and high-complexity clinical assistance.
A clear and structured process
Your pathway in 5 steps
1. Free introductory video call
Everything starts with a free video call. You will speak directly with Tommaso Martella, Patient Care Manager at PSV. During the call, you will be able to explain your situation, share your previous diagnoses and treatments, understand how our CRPS pathway works, and receive realistic information about next steps, timing, and approximate costs.
This is not a sales call. It is a first conversation focused on clarity, trust, and understanding whether our approach may be appropriate for your case.
2. Medical record review
If you decide to move forward, we help you organize the medical information needed for evaluation. This may include imaging, reports, lab results, and previous specialist documentation. Our team reviews your records in advance so that your time in Verona is used as efficiently and meaningfully as possible.
3. Planning your visit to Verona
We are a clinic, not a travel agency. If needed, we can provide practical suggestions to help you plan your stay in Verona, including general guidance on accommodation and local logistics. Our role is to help you prepare for treatment clearly and realistically, while keeping the medical pathway at the center.
4. In-clinic evaluation and treatment
At PSV, your pathway includes a multidisciplinary clinical evaluation, diagnostic confirmation or refinement, and a structured treatment protocol centered on a cycle of 4 intravenous Neridronate infusions. Based on the clinical profile of each patient, the treatment pathway may also be strengthened with Clodronate infusions, infusion-based vitamins and coenzymes, rehabilitation support, and targeted gut microbiota modulation strategies, an area in which our team has dedicated expertise.
Every decision is explained clearly, so the patient understands why each part of the protocol is being proposed.
5. Follow-up and continuity of care
Your care pathway does not end when you return home. We can provide medical documentation for your local physicians, remote follow-up, and clinical guidance as your pathway progresses. The objective is continuity, not a one-time intervention.
"At PSV, the CRPS pathway is not a medical travel package — it is a structured clinical protocol centered on the patient."
No obligation. Speak directly with the clinic.
FAQ
Practical answers before you reach out
No. Patients may contact PSV with a suspected or confirmed diagnosis if they are looking for a clearer clinical assessment and information on the pathway.
Yes. The introductory video call is free and designed to help the patient understand the process, ask questions, and decide whether to move forward.
Directly with the clinic.
PSV is a clinic, not a travel agency. If needed, practical suggestions can be provided, but the focus remains on treatment.
Yes. The goal is to provide clear information on the medical pathway, practical steps, and approximate costs before the patient travels.
Request your free introductory call
Contact the clinic directly
If you are a U.S. patient living with CRPS and looking for clearer answers, a more structured treatment pathway, and direct contact with a specialized clinic, we invite you to contact us.
Prefer email?
t.martella@polispecialisticoverona.it
You will be contacted with the information needed to understand the next step clearly.
POLIAMBULATORIO SPECIALISTICO VERONA
Viale del Lavoro 25/a
37135 Verona (VR), Italy
Medical Director: Dott. Fabrizio Martella
Address
Contacts
© 2026 Poliambulatorio Specialistico Verona S.R.L. — P.IVA 03504300231 Informational only. Not medical advice.